A label-free amplified fluorescence DNA detection based on isothermal circular strand-displacement polymerization reaction and graphene oxide.

نویسندگان

  • Zhen Li
  • Wenping Zhu
  • Jinwen Zhang
  • Jianhui Jiang
  • Guoli Shen
  • Ruqin Yu
چکیده

A label-free fluorescent DNA biosensor has been presented based on isothermal circular strand-displacement polymerization reaction (ICSDPR) combined with graphene oxide (GO) binding. The proposed method is simple and cost-effective with a low detection limit of 4 pM, which compares favorably with other GO-based homogenous DNA detection methods.

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عنوان ژورنال:
  • The Analyst

دوره 138 13  شماره 

صفحات  -

تاریخ انتشار 2013